![]() These four nucleobases were probably not abundant on the early Earth, and conventional base pairing with the four canonical nucleobases does not occur in water, so then how could RNA exist? Another refresher for people not so familiar with DNA and RNA: a base pair is a pair of complementary nucleobases joined by weak hydrogen bonds. The ribose itself would have rapidly degraded if not used quickly, but the larger problem is that conditions were not conducive for the formation of nucleosides from ribose and the four canonical RNA nucleobases (adenine, guanine, cytosine, and uracil). The five-carbon sugar that forms the backbone of RNA is ribose.įorming RNA from the ribose produced from chemical evolution poses some problems, however. These sugars essentially form the backbones of DNA and RNA. A nucleotide is a nucleoside with an attached phosphate group, and a nucleoside is a nitrogenous base/nucleobase attached to a five-carbon sugar. At their foundations, RNA is typically composed of a single strand/chain of nucleotides whereas DNA is composed of two antiparallel strands/chains of nucleotides. First off, here is some preliminary information for those of you not overly familiar with DNA or RNA. The current leading hypothesis states that RNA evolved before DNA as the primary genetic material for early life, and even before RNA there likely existed some even simpler genetic system, but we will focus on the better understood RNA system. No matter the source, once present on Earth, chemical evolution drove the synthesis of amino acids, ribose and other sugars, and other important chemical components of life from simpler ingredients, but before the emergence of more conventional deoxyribonucleic acid (DNA) based life, there existed a ribonucleic acid (RNA) world. The Earth was either seeded by meteors already carrying simple organic matter (pseudo-panspermia), or organic matter formed on Earth such as around deep sea hydrothermal vents. Most hypotheses for their sources fall into one of two categories: extraterrestrial or terrestrial origins. Of course these chemical ingredients had to come from somewhere. Many experiments, beginning with those of Stanley Miller in 1953, have shown that given the right mix of chemicals, liquid water, and energy, simple molecules will combine and rearrange to form complex organic matter such as the amino acids essential to life. If a cycle involved in self-replication diverges into two different cycles where one cycle produces the same molecule at a higher rate using the same materials, then this new cycle should outcompete and replace the original cycle. ![]() Self-replication inevitably gives rise to relatedness among molecules. The appearance of self-replicating molecules is key to further chemical evolution. The process gave rise to self-replicating molecules, provided the building blocks for life, and eventually led to the emergence of the first organisms. To be a bit more specific, chemical evolution explains the synthesis of organic matter from inorganic molecules followed by the increasing complexity of lifeless organic matter over time. Chemical evolution is the evolution of lifeless organic matter. So what is chemical evolution? It is not the evolution of life. Now you may be thinking to yourself “if life could not exist for the first 400-600 million years, the Earth is roughly 4.6 billion years old, and life does not appear until around 3.6 billion years ago, that still leaves another 400-600 million years unaccounted for.” What was occurring during this period of time you ask? The answer: chemical evolution. Sure enough, fossil records indicate the existence of cellular life around 3.6 billion years ago. Once these extreme conditions lessened to a large enough degree, however, life could take shape. Until its molten surface cooled allowing the crust to form and meteor strikes became less frequent, the development and sustenance of life would be virtually impossible. At its inception, and for a period afterwards, our planet had a molten surface under constant bombardment from meteors. ![]() Evidence suggests that the Earth was a largely inhospitable place for the first 400-600 million years of its existence. Conditions on Earth were not immediately suitable for life, nor did life originate late in its geologic history. A less common misconception involves just how long Earth has been habitable. Thanks to the efforts of modern science, we know the Earth to be around 4.6 billion years old. Earth’s age is not in the order of thousands, hundred of thousands, or millions of years. Our planet’s approximate age is a surprisingly common misconception among the public today.
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